PHARMACOKINETICS OF EVOCALCET IN SECONDARY HYPERPARATHYROIDISM PATIENTS RECEIVING HEMODIALYSIS: FIRST-IN-PATIENT CLINICAL TRIAL IN JAPAN

Pharmacokinetics of evocalcet in secondary hyperparathyroidism patients receiving hemodialysis: first-in-patient clinical trial in Japan

Takashi Shigematsu,1 Ryutaro Shimazaki,2 Masafumi Fukagawa,3 Tadao Akizawa4 On behalf of the Evocalcet Study Group 1Department of Nephrology, Wakayama Medical University, Wakayama, Japan; 2R&D Division, Kyowa Hakko Kirin Co., Ltd., Chiyoda-ku, Tokyo, Japan; 3Department of Internal Medicine, Division of Nephrology, Endocrinology and Metabolism,

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NArchitecTURE: A Paradigm of Design with Nature

The relationship between architecture and nature has been a constant debate in the field.The preposition that architecture is an integral part of nature and even the natural landscape itself has accompanied the development of architectural theories over time.However, the question of how nature can be a 100w products design language intrinsically in

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Aberrant Spontaneous Brain Activity and its Association with Cognitive Function in Non-Obese Nonalcoholic Fatty Liver Disease: A Resting-State fMRI Study

Background: Nonalcoholic fatty liver disease (NAFLD) has been proven to be associated with an increased risk of cognitive impairment and dementia, and this association is more significant in non-obese NAFLD populations, but its pathogenesis remains unclear.Our study aimed to explore the abnormalities of spontaneous brain activity in non-obese NAFLD

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